BDBM14031 5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinolin-1-one::CHEMBL1233300::HA-1100::Hydroxyfasudil

SMILES O=c1[nH]ccc2c(cccc12)S(=O)(=O)N1CCCNCC1

InChI Key InChIKey=ZAVGJDAFCZAWSZ-UHFFFAOYSA-N

Data  4 KI  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14031   

TargetC-C motif chemokine 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibition of MCP1-mediated human THP cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed